Claro Otic

Claro otic is an extended-action treatment for acute otitis externa in dogs. The active ingredients include florfenicol (antibiotic), terbinafine (antifungal), and mometasone furoate (anti-inflammatory). It is FDA-approved for one-time treatment of otitis externa in dogs with Malassezia pachydermatitis and/or Staphylococcus pseudointermedius. In a blinded, controlled study of 221 dogs with otitis, successful treatment was achieved in 72.5% of dogs.


  • Dog with otitis externa due to yeast and/or cocci (but not rods)
  • Claro Otic must only be used if the tympanic membrane in intact


  • Not approved for use in cats
  • Bacterial infection with rods visible on ear cytology
  • Perforation of the tympanic membrane or inability to visualize the tympanic membrane
  • Known sensitivity to any of the components

Side effects/risks

  • Deafness and vestibular signs – if tympanic membrane not intact
  • Suppression of the adrenocortical axis, leading to systemic signs of hyperadrenocorticism (noted in research dogs treated with at least 3x overdose over 28 days)

How to use

This product is ONLY to be administered by a veterinarian while the pet is in the clinic/hospital.

  1. Clean and dry the affected ear canal. Visualize the intact tympanic membrane.
  2. Remove cap from single dose tube. Attached the applicator nozzle.
  3. Apply entire 1ml dose into the ear canal and gently massage to distribute medication.
  4. Instruct the owners NOT TO CLEAN the ear at home for the entire 30 days after application.

For unilateral infections, apply a single vial to the ear canal. If the infection is bilateral, a separate tube must be used for each ear. The client must be charged for two tubes.

How to charge for this product

Since it is applied by a veterinarian in-office and NOT dispensed, it is charged as a treatment code and the charge should go to the doctor who administers it.  When applying, the entire tube (consisting of 1 ml) is applied into the ear canal. If applying bilaterally, a charge must be entered for each vial.

Last updated: 2017-03-09